基于支撐雙分子層膜的智能生物傳感器系統(tǒng)研究.pdf

1、分類號UDC密級學(xué)號蓼795898彳磨火季博士學(xué)位論文論文題目：基于支撐雙分子層膜的智能生物傳感器系統(tǒng)研究論文作者：劉盛平誓嘉、≈‰警需韋云隆教授重慶大學(xué)職稱、工作單位：韋石陛教搜重伏天罕申請學(xué)位級別：博士學(xué)科、專業(yè)名稱i機械設(shè)計及理論論文提交日期：2003年4月28日答辯日期：2003年10月30日學(xué)位授予單位：重慶大學(xué)授位日期：年月日答辯委員會主席：黃茂林教授論文評閱人：鄒慧君馮培恩張湘?zhèn)ソ蜏卦婅T蔡紹皙李祖樞2003年4月28日英

2、文摘要ABSTRACTThemoditicationandsensingcharacteristiCSofelectrodesbasedonsBLM(supportedBilayerLipidMembrane)totypicalionswereleamtbyanumberofexperimentalinvestigationsThedissertationadvancedanovelfabricationtechnicsandmetho

3、dofSBLMTheadvantagesofthenewfabricationmethodwerecontrastivelyanalyzedthroughexperimentsThesensingmechanismofbiosensorssBLMbasedandthemechanismofmodifieractionwereanalyzedThesystembasedonsBLMswassimulatedandanalyzedusing

4、numericalmethodThefimdamentalresearchandapplicationwerecarriedout111edissertationproposedtheconceptofwirelessintelligentbiosensoranddevelopedasBLMbasedbiosensorsystemAdataacquisitionmoduleandwirelesstransceivemoduleofthe

5、sBLMbasedbiosensorsystemwasbasicallyperformedAnintelligentizedbiosensorsystembasedonsBLMwasdevdopedOnthebasisofresearch，thesystematicconfigurationofthewirelessintelligentbiosensorsystemwasconstructedBLMs，alikethebilayers

6、tructureofbiomembrane，possessbiologicalcompatibilityItispronetobemodifiedFunctionalmoleculescarlbeconvenientlyembeddedintoBLMsBythiswayBLMsmodifiedbydifferentfunctionalmoleculesCaneasilydetectthecounterpartsexistinginsol

7、utionInthisdissertationmodificationandsensingcharactersofdifferentmodifiers，includingvalinomycin，crownether12andfullerenes(C60／C70)etc，werestudiedTheauthorresearchedthetemperatureimpactonthecurrent—voltagecharacteriticso

8、fSBLMAnewcriterionODmembranesformedPhaseTransformationTemperatureWasgivenAnovelfabricationmethodofsBLMwasreportedinthisdissertationApreliminarystudyontheinfluenceofmechanicalcharacteristicsofsubstratesection，includingsmo

9、othnessandareaofsubstratesectiontotheelectricalpropertyofSBLMwasperformedUsingmicroscope，thedissertationcomparedthemicrocosmiccharacteristicsofinterfacestreatedbythenovelfabricationmethodgiveninthispaperandtraditionalmet

10、hod，respectivelyApreliminaryresearchontheinfluenceofthesmoothnessofsubstratesectiontothecharacteristicsofsBLMwasperformedutilizingCyclicVoltammetry(cv)Theresultshadicatethatthenewmethodovercomethedisadvantagethattheprobe