膜聯蛋白A1在小細胞肺癌骨轉移中的作用及分子機制的研究.pdf

1、 博士學位論文膜聯蛋白 膜聯蛋白 A1 在小細胞肺癌骨轉移中的作用 及分子機制的研究 在小細胞肺癌骨轉移中的作用 及分子機制的研究 張 峰 培 養(yǎng) 類 別 全日制 學 位 類 型 學術學位 一級學科(專業(yè)類) 臨床醫(yī)學 二 級 學 科 ( 專 業(yè) ) 腫瘤學 研 究 方 向 肺癌骨轉移相關機制 指 導 教 師 張賀龍 教授（主任醫(yī)師） 培 養(yǎng) 單 位 唐都醫(yī)院腫瘤科 二 O 一三年五月 分 類 號 U D C 密

2、級 第 四 軍 醫(yī) 大 學The Fourth Military Medical University第四軍醫(yī)大學博士學位論文 目 錄 縮略語表························&

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22、·························27 實驗一 膜聯蛋白 A1 在不同骨轉移潛能小細胞肺癌細胞株中的表達 ·····

23、83;············27 1 材料........................................................................................................................ 28 2 方法..........

24、.............................................................................................................. 30 3 結果......................................................................................................

25、.................. 35 4 討論........................................................................................................................ 36 實驗二 膜聯蛋白 A1 在小細胞肺癌細胞中的生物學作用·······

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28、. 42 3 結果........................................................................................................................ 53 4 討論...................................................................................

29、..................................... 65 實驗三 膜聯蛋白 A1 促進小細胞肺癌骨轉移機制的初步探討 ························

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