人骨髓間充質干細胞對肺癌細胞增殖轉移及自噬凋亡的調控作用研究.pdf

1、博士學位論文人骨髓間充質干細胞對肺癌細胞增殖轉移及自噬凋亡的調控作用研究張明慧指導教師胡義德教授、主任醫(yī)師導師組成員胡義德王志新孫建國培養(yǎng)單位第三軍醫(yī)大學新橋醫(yī)院全軍腫瘤研究所申請學位類別博士學術學位專業(yè)名稱腫瘤學論文提交日期2013年4月論文答辯日期2013年5月答辯委員會主席畢鋒評閱人蔣耀光王閣吳德華焦順昌張賀龍二〇一三年五月分類號分類號R734.2密級公開學開學號1002009107學校代碼學校代碼90031目錄縮略語表.....

2、.........................................................................................................................1英文摘要..............................................................................................

3、................................3中文摘要..............................................................................................................................8論文正文人骨髓間充質干細胞對肺癌細胞增殖轉移及自噬凋亡的調控作用研究...12第一章前言............

4、...........................................................................................12第二章人骨髓間充質干細胞的分離培養(yǎng)及鑒定....................................................162.1引言................................................

5、..........................................................162.2材料與方法...................................................................................................162.3實驗結果............................................

6、..........................................................202.4討論..........................................................................................................232.5小結..........................................

7、................................................................25第三章hMSCs對肺癌細胞增殖能力影響的體內外實驗研究................................263.1引言........................................................................................

8、......................263.2材料與方法...................................................................................................263.3實驗結果................................................................................

9、......................353.4討論..........................................................................................................423.5小結..............................................................................

10、............................44第四章hMSCs對肺癌細胞侵襲轉移能力的體內外實驗研究................................454.1引言..........................................................................................................454.2材料與方法........

11、...........................................................................................454.3實驗結果......................................................................................................504.4討論...........

12、...............................................................................................544.5小結..........................................................................................................57第五章hMSCs對肺

13、癌細胞自噬與凋亡的調控作用..............................................585.1引言..........................................................................................................585.2材料與方法......................................

14、.............................................................585.3實驗結果......................................................................................................665.4討論.........................................